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NORTHERN CALIFORNIA BRANCH OF THE AMERICAN ASSOCIATION FOR LABORATORY ANIMAL SCIENCE 

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Contact:  Caroline Sepulveda at sepulveda.caroline@gene.com 


Title: Senior Supervisor / Manager, In Vivo Surgery at Ambys Medicines
Location: South San Francisco, CA

POSITION SUMMARY
Our In Vivo Sciences team is growing and has an exciting opportunity for a talented and motivated Senior Supervisor/Manager, In Vivo Surgery. You will contribute as part of a multidisciplinary team to develop novel therapies to treat liver diseases using cell and gene therapy strategies. In this role, you will report to our Senior Director, In Vivo Sciences/Attending Veterinarian and will be responsible for high quality delivery of animal models.

Click here for more information

What you will do:

  • Operate at the highest standards for best veterinary practices in the conduct of research surgery
  • Identify methodology to ensure the development of animal models meets animal welfare standards and produces reproducible results
  • Develop and deliver surgical animal models for early discovery through preclinical development
  • In conjunction with Animal Program leadership, develop with and maintain standard operating procedures, policies and guidelines pertaining to surgery, anesthesia and analgesia; generate and revise IACUC Policies
  • Lead and train colleagues, and thrive in a matrixed team environment
  • Develop, foster and maintain collaborative relationships with internal and external groups/departments, agencies and other organizations associated with the program

Qualifications:

  • Bachelor's degree (B.A. /B.S.) with considerable knowledge of relevant animal welfare guidelines as it pertains to laboratory species, and an understanding of the drug development process
  • 7+ years experience in surgical model development and production, with prior background working in a contract research or biopharmaceutical laboratory animal vivarium.
  • 5+ years direct supervision of technical staff
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • AALAS certification at the Laboratory Animal Technologist (LATG) level; Academy of Surgical Research certification preferred
  • Registered Veterinary Technician (RVT) in the state of CA, or equivalent is preferred
  • Experience working in an animal program adhering to regulatory and accreditation standards (USDA, OLAW, FDA, AAALAC etc.)
  • Deep knowledge and technical proficiency of animal physiology/anatomy, recognition of normal/abnormal behavior, clinical problems and animal welfare issues with in vivo procedures
  • Ability to implement changes to department processes/procedures and build strong partnerships across the organization.


Company Description:
Ambys Medicines is a biotechnology company focused on discovering and developing regenerative and restorative therapies for people with advanced liver disease. Founded by world-renowned experts in liver disease and regenerative medicine, Ambys is pioneering the application of novel modalities including cell and gene therapy, and gain-of-function drug therapy, to meet the urgent need for treatments that have the potential to restore liver function and prevent the progression to liver failure across multiple liver diseases that are untreatable or poorly treated today. Ambys was launched in 2018 by Third Rock Ventures and Takeda Pharmaceuticals with $140M in starting capital and is headquartered in South San Francisco, California.


To apply: https://grnh.se/fd6ca3ab2us
For more information, email: Krystle Okialda

(Posted 10/16/20)


Title: Senior Manager, IACUC Administration and Compliance at Ambys Medicines
Location: South San Francisco, CA

POSITION SUMMARY
Our In Vivo Sciences team is growing and has an exciting opportunity for a talented and motivated Senior Manager, IACUC Administration and Compliance. You will contribute as part of a multidisciplinary team to develop novel therapies to treat liver diseases using cell and gene therapy strategies. In this role, you will report to our Senior Director, In Vivo Sciences/Attending Veterinarian and will be responsible for refining and implementing IACUC administration, partnering with Vivarium Operations to develop and lead our training program.

Click here for more information

What you will do:

  • Coordinate and facilitate IACUC activities across involved teams in support of R&D programs, schedule/run IACUC meetings, review IACUC Protocols/Amendments, and help generate reports for regulatory submissions
  • Help develop and maintain vivarium standard operating procedures, policies and guidelines; update as needed to ensure compliance with the animal care and use program
  • In conjunction with IACUC Chair and Attending Veterinarian, generate and revise IACUC Policies
  • Identify deficiencies and recommend solutions for record management as it pertains to the Animal Care Program
  • Assure competency assessments and provide technical training (animal handling, dose administration, blood and tissue collections, euthanasia) and general expertise to animal users when needed
  • Develop, foster and maintain collaborative relationships with internal and external groups/departments, agencies and other organizations associated with the program

Qualifications:

  • Bachelor's degree (B.A. /B.S.) with considerable knowledge of relevant animal welfare guidelines as it pertains to laboratory species, and an understanding of the drug development process
  • 8+ years relative experience with prior background working in a laboratory animal environment. An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • AALAS certification at the Laboratory Animal Technologist (LATG) level
  • Certified Professional IACUC Administrator (CPIA) or equivalent certification preferred
  • Compliance experience working in an animal program adhering to regulatory and accreditation standards (i.e. USDA, OLAW, FDA, AAALAC etc.).
  • Deep knowledge and technical proficiency of animal physiology/anatomy, recognition of normal/abnormal behavior, clinical problems and animal welfare issues with in vivo procedures.
  • Ability to implement changes to department processes/procedures and build strong partnerships across the organization.


Company Description:
Ambys Medicines is a biotechnology company focused on discovering and developing regenerative and restorative therapies for people with advanced liver disease. Founded by world-renowned experts in liver disease and regenerative medicine, Ambys is pioneering the application of novel modalities including cell and gene therapy, and gain-of-function drug therapy, to meet the urgent need for treatments that have the potential to restore liver function and prevent the progression to liver failure across multiple liver diseases that are untreatable or poorly treated today. Ambys was launched in 2018 by Third Rock Ventures and Takeda Pharmaceuticals with $140M in starting capital and is headquartered in South San Francisco, California.


To apply: https://grnh.se/6408aa0c2us
For more information, email: Krystle Okialda

(Posted 10/16/20)


Title: Assistant Research Scientist II (Pharmacology) at Exelixis
Location: Alameda, CA

SUMMARY:
The successful and highly motivated candidate will support the in vivo pharmacology research program and contribute to the multidisciplinary research team by designing and executing in vivo studies to determine pharmacokinetics and pharmacodynamics relationships and efficacy of optimized leads.

ESSENTIAL DUTIES AND RESPONSIBILITIES:
  • Assist in the planning, design and implementation related to animal studies of pharmacokinetics, pharmacodynamics, and efficacy to evaluate and differentiate lead validation and lead optimization programs under general supervision
  • Compliance with IACUC protocols and AAALAC regulations in conducting general research duties within assigned area of responsibility
  • Prepare and organize data for presentation using analysis and visualization software; present data and reports on project status at individual, group, and departmental research meetings under general supervision
  • Maintain familiarity with current scientific literature relevant to the research experiments or programs
  • Maintain laboratory notebook in a complete, consistent, and concise manner in accordance with company intellectual property policies and practices
  • Adhere to good health and safety practices and compliance with applicable EH&S rules, and participating in mandatory safety training programs
Click here for more information

Division: Discovery
Department: Biology
Reports To: Senior Scientist, Pharmacology
FLSA Status: Exempt
Effective Date: December 2019


EDUCATION/EXPERIENCE/SKILLS:
Education:

  • BS in a relevant biological scientific discipline and two to four years of related experience; or,
  • MS in a relevant biological scientific discipline and zero to two years of related experience
  • Equivalent combination of education and experience
Experience:
  • Proficiency with in vivo techniques including iv, ip, sc, po administration, and blood collection (tail vein, retroorbital, cardiac puncture, submandibular and etc.) is required
  • Proficiency in animal tumor model development and execution including but not limited to syngeneic, xenograft and humanized mouse model is essential
  • Good practice with in vitro sterile cell culture and scale-up for tumor implantation is required
  • Ability to conduct organ harvesting; transcardial perfusion and fixation from small animals
  • Adept at sample processing, homogenization, or generation of single-cell suspensions for ex vivo analysis
  • Experience with immunology-related biological assays, flow cytometry, MSD and Luminex is a plus
  • Excellent data analysis skills and experience with a variety of scientific software applications is preferred
  • Proficiency with computers including MS Word, MS PowerPoint, and MS Excel is required
Knowledge/Skills/Abilities:
  • General knowledge of pharmacokinetics, pharmacology and immunology techniques, theories, and practices
  • General understanding of how the individual experiments fit within a larger research program to meet organizational goals
  • General understanding and application of scientific principles, theories and concepts in field of specialty and other related disciplines
  • Ability to perform in a fast-paced environment and be flexible
  • Ability to adapt to changing work conditions
  • Must be self-motivated, able to multi-task and detail-oriented
  • Strong communication skills, excellent work ethic, self-motivation, and ability to work effectively in a either a team environment or independently
  • Understanding of regulatory requirements to run an in vivo facility
  • Collaborate with other project team members

JOB COMPLEXITY:
  • Work on problems of diverse scope where analysis of data requires evaluation of identifiable factors
  • Exercise judgment within generally defined practices and policies in selecting methods and techniques for obtaining solutions
  • Use professional concepts and company policies and procedures to solve a wide range of difficult problems in imaginative and practical ways

DISCLAIMER:
The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

Company website: https://www.exelixis.com/careers/

To apply, email resumes to: bcoe@exelixis.com

(Posted 9/10/20)


Title: Assistant Research Scientist I (Pharmacokinetics/Pharmacodynamics) at Exelixis
Location: Alameda, CA

SUMMARY:
The successful and highly motivated candidate will support the in vivo pharmacology research program and contribute to the multidisciplinary research team by designing and executing in vivo studies to determine pharmacokinetics and pharmacodynamics relationships and efficacy of optimized leads.

ESSENTIAL DUTIES AND RESPONSIBILITIES:
  • Conduct in vivo studies in mouse and/or rat models to assess pharmacological characteristics of preclinical drug candidates.
  • Daily dosing (po, iv, ip) of preclinical drug candidates to mice or rats, followed by blood and tissue collection for pharmacokinetic or pharmacodynamic analyses.
  • Tumor implantation and measurement for long-term efficacy and pharmacodynamic studies.
  • Use of aseptic techniques to grow and scale up tumor cells for implantation in mouse models.
  • Assist in planning, design and implementation related to animal studies of pharmacokinetics, pharmacodynamics, and efficacy studies to evaluate and differentiate lead validation and lead optimization programs under general supervision
  • Prepare and organize data for presentation using analysis and visualization software; present data and reports on project status at individual, group, and departmental research meetings under general supervision
  • Maintain familiarity with current scientific literature relevant to the research experiments or program
  • Maintain laboratory notebook in a complete, consistent, and concise manner in accordance with company intellectual property policies and practices
  • Adhere to good health and safety practices and compliance with applicable EH&S rules, and participate in mandatory safety training programs
Click here for more information

Division: Discovery
Department: 10231 Discovery Biology
Reports To: Scientist I
FLSA Status: Exempt
Effective Date: June 2020


SUPERVISORY RESPONSIBILITIES:
None

EDUCATION/EXPERIENCE/SKILLS:
Education:

  • Bachelor’s degree (B.A./B.S.) in related discipline and up to two years of relevant experience; or
  • Equivalent combination of education and experience.
Experience:
  • Proficient with in vivo techniques including animal handling, dosing methods (iv, ip, sc, po), blood collection techniques (tail vein, RO, cardiac puncture, etc.), tumor implantation and measurement, and tissue collection from small laboratory animals.
  • Experience with aseptic technique, in vitro cell culture and cell culture scale-up for implantations is preferred.
  • Experience handling and processing biological samples in a laboratory setting.
  • Excellent data analysis skills and experience with a variety of scientific software applications is preferred.
  • Proficiency with computers including MS Word, MS PowerPoint, and MS Excel is required. Experience with GraphPad Prism and StudyLog software is preferred.
Knowledge/Skills/Abilities:
  • General knowledge of pharmacokinetics, pharmacology and vivarium techniques, theories, and practices.
  • General understanding of how individual experiments fit within a larger research program to meet organizational goals.
  • General understanding and application of scientific principles, theories and concepts in field of specialty and other related disciplines.
  • Strong communication skills, excellent work ethic, self-motivation, and ability to work effectively in a either a team environment or independently.
  • Collaborate with other project team members.

JOB COMPLEXITY:
  • Work on problems of diverse scope where analysis of data requires evaluation of identifiable factors.
  • Exercise judgment within generally defined practices and policies in selecting methods and techniques for obtaining solutions.

DISCLAIMER:
The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

Company website: https://www.exelixis.com/careers/

To apply, email resumes to: bcoe@exelixis.com

(Posted 9/10/20)


Title: Senior Laboratory Animal Veterinarian at Genentech, Inc.
Location: South San Francisco, CA

Job ID: 201912-136696

We are seeking an experienced laboratory animal veterinarian to join the Animal Resources department and expand our team. Our mission is to provide excellent service and support for Genentech’s in vivo research program. We collaborate with and provide expert support to our research scientists in the discovery, characterization, and development of novel therapeutic products for a variety of human diseases. We are dedicated to providing excellent animal care, progressive veterinary medicine, and expert lab animal science knowledge. This is an opportunity to join our team during a time of exploration and growth in areas such as microbiome and alternative in vivo models. This position reports directly to the Attending Veterinarian/Director of Animal Resources.

Click here for more information

Qualifications:

In hiring new employees, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture. Because we know that employees are critical to our success in bringing novel medicines to patients, we are dedicated to remaining a great place to work and to providing employees with programs, services and benefits that allow them to bring their best to the business and to their personal lives. We are looking for a team player who is a creative, independent thinker, thrives in a widely interdisciplinary environment, and enjoys working closely and communicating effectively with colleagues in extremely diverse fields.

The ideal candidate will be ACLAM board certified, board eligible, or have advanced experience and expertise in the area of lab animal medicine. The candidate must have the ability to obtain a veterinary medical license in California.

The ideal candidate will have experience in building and leading teams, managing people and animal research facilities, and have strong interpersonal and communication skills.

The ideal candidate will have experience providing excellent clinical and surgical care in the lab animal field, including transgenic rodents, providing technical support to research projects, collaborating with researchers, ensuring compliance with federal regulations and AAALACi standards, and training/teaching research and lab animal staff.

This position is located in SSF, but willingness to collaborate across time zones and occasional travel to the Dixon facility is a must.


Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.


(Posted 9/10/20)


Title: Lab Manager, Tsao Lab at UC Berkeley
Location: Berkeley, CA

Job overview:
The Tsao Lab, currently located at Caltech in Pasadena, CA, will be relocating to UC Berkeley. We are seeking a Lab Manager (starting August 1, 2021 at UC Berkeley, with a possibility to start as early as October 1, 2020 at Caltech and then move to Berkeley). The candidate should have experience in one or more of the following: animal husbandry, animal surgery, animal behavior and/or training, biomedical research, and laboratory management. An interest in working with non-human primates is an absolute must. Personal qualities essential for this job include: sense of responsibility, excellent organizational skills, love for working with animals, and desire to contribute to understanding the brain. Preference for candidates with a BS. Candidates with vet tech qualifications are especially desired. Salary negotiable depending on experience.

Click here for more information

Our lab:
The Tsao lab (http://tsaolab.caltech.edu/) studies the neural mechanisms underlying vision in non-human primates and mice. We study questions related to object recognition, spatial perception, memory, and consciousness. We use multiple approaches including functional MRI (fMRI), electrophysiology, widefield and two-photon imaging, and mathematical modeling.

Work with Non-Human Primates:
The job will involve hands-on coordination of our animal colony (overseeing the health and welfare of the animals, interfacing with animal care and veterinary staff), assisting with surgeries and anesthesia, preparing and administering medications, and training animals on behavioral tasks.

Research and Management:
The Lab Manager will assist with fMRI experiments and other ongoing projects in the lab. Responsibilities also include purchasing and maintenance of equipment and supplies and maintenance of laboratory records. The Lab Manager also coordinates projects with other offices and labs on campus to ensure compliance and safety.


For more information or to apply, please email Doris Tsao (dortsao@caltech.edu). Please include a CV and contacts of at least two references in your application.


(Posted 8/24/20)


Title: Animal Care Technician II at Apex Systems
Location: South San Francisco, CA or Dixon, CA

Essential duties and responsibilities:
  • Monitor daily animal health and welfare while performing daily animal health observations utilizing an assigned iPAD or tablet device.
  • Perform animal husbandry duties to maintain quality and health of research animals, to include: perform daily water bottle /automatic water line and cage checks; provide appropriate food and water; perform cage changing and/or cage cleaning as required; record animal health concerns per SOP and/or specified protocols.
  • Work closely with Veterinary Staff, assist with animal sample collection and other in vivo procedures as assigned by the on-site facility veterinarian or veterinary staff member.
  • Provide service daily to the researchers to ensure study animals receive medicated diet and/or water and any other special housing requests outlined in their study protocol. Direct communication and interaction may be required between employee and researcher.
  • Perform a variety of technical procedures on rodents, such as, ear tagging, shaving, blood collecting, tissue sampling, glucose monitoring, fasting, etc.
  • Strictly follow all procedures necessary to maintain animal housing areas or isolator environments, including room or facility personnel entry and personnel protective equipment use, biosecurity procedures.
  • Receive, inspect and house incoming animals; care for and provide for sentinel animals in each rodent housing area as required by department SOP’s, guidelines/policies, and protocols.
  • Operate equipment and use supplies according to safety guidelines; perform general housekeeping and adheres to safety procedures.
  • Perform all other related duties as assigned.
Click here for more information

Benefits of being an Apex Employee:

  • One Paid AALAS Certification (ALAT, LAT, LATG)
  • PTO, Sick Time and Holiday pay
  • Attendance and performance incentives and team building activities
  • Medical, Vision and Dental coverage options
  • Long and Short Term Disability, Life Insurance, Employee Stock Purchase Plan, 401(k) plan, Transit Account and additional Insurance offerings

Qualifications:
Education: High school diploma, General Education Degree (G.E.D.) or equivalent required.
Experience: ALAT Certification preferred and/or a minimum of two years directly related laboratory animal experience in an AAALAC accredited facility.
An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.


For a full job description as well as additional information please reach out to Alicia Marshall at asmarshall@apexsystems.com

(Posted 8/14/20)


Title: Animal Care Technician I at Apex Systems
Location: South San Francisco, CA or Dixon, CA

Essential duties and responsibilities:
  • Operates cage wash equipment and uses supplies according to safety guidelines; performs general housekeeping and adhere to safety procedures.
  • Cleans and sanitizes all animal caging and accessory equipment and maintains the cage washing area in a clean, neat and well-organized manner following approved SOP’s and/or department guidelines/policies.
  • Disposes of all waste materials, including biohazard and hazardous waste, in a safe and thorough manner as required.
  • Maintains facility equipment and performs routine preventative maintenance on cage washers, including routine inspection of cleaning filters, following approved SOP’s and/or department guidelines/policies.
  • Assists with the receipt, stocking inventory, and maintenance of supplies.
  • Performs other duties as assigned.
Click here for more information

Benefits of being an Apex Employee:

  • One Paid AALAS Certification (ALAT, LAT, LATG)
  • PTO, Sick Time and Holiday pay
  • Attendance and performance incentives and team building activities
  • Medical, Vision and Dental coverage options
  • Long and Short Term Disability, Life Insurance, Employee Stock Purchase Plan, 401(k) plan, Transit Account and additional Insurance offerings

Qualifications:
Education: High school diploma or GED required.
Experience: Rodent husbandry experience preferred. ALAT certification preferred. ALAT testing/certification required within 24 months of employment. Previous experience performing housekeeping/sanitization duties, safe handling of chemicals, detergents and disinfectants according to MSDS guidelines and working with large industrial equipment, especially cagewash equipment, preferred.


For a full job description as well as additional information please reach out to Alicia Marshall at asmarshall@apexsystems.com

(Posted 8/14/20)


Title: Associate Director / Director, Vivarium Operations at Ambys Medicines
Location: South San Francisco, CA

POSITION SUMMARY
Our In Vivo Sciences team has an exciting opportunity for a talented and motivated Associate Director/Director to lead and ensure successful operational management of two vivarium physical plants. You will contribute as part of a multidisciplinary team to develop novel therapies to treat liver diseases using cell and gene therapy strategies. In this position, you will be responsible for ensuring daily and strategic operational maintenance of animal facilities, supervision of animal care staff, and ensuring appropriate animal care to laboratory animal species in accordance with institutional, local and federal regulations. You will work closely with the Attending Veterinarian, peers and senior management to support our company strategy, provide oversight of the program of animal care, sustain successful supplier partnerships, ensure day-to-day support for science, and maintain the vivarium physical plant (not to exclude commissioning and validation functions) success.

Click here for more information

Qualifications:

  • 2 or 4-year degree in basic science, animal science, or veterinary science with 8+ years of experience in a vivarium supervisory role with management/leadership responsibilities
  • MA, MS, MBA, or other advanced degree in related scientific/business management field highly desirable
  • AALAS-LATg, CMAR, ILAM, and/or CPIA (or international equivalent)
  • Management of vivarium under GLP or GMP compliance, BSL-2 and/or breeding of immune-compromised animal models
  • Familiar with working in a matrix environment with reporting responsibilities to Attending Veterinarian, compliance and quality assurance roles, and the Executive Committee
  • Optimization of vivarium roles and functions including but not limited to colleague development and job expectations
  • Management of business processes (i.e. SOPs, metrics, cost of ownership etc,) and reporting of vivarium operational efficiencies, workplace safety, preventative maintenance and cost analyses in responsible areas
  • Past participation on IACUC committee and/or semi-annual inspections is desirable
  • Possess working depth of knowledge and compliance with the Guide (2011) and direct participation with AAALAC site visitors
  • Exercises excellent organizational, interpersonal and communication skills to build collaborative relationships, a strong commitment to providing quality research scientific support, and humane animal care in accordance with guidelines and regulations pertaining to Laboratory Animal Care
  • Works effectively as a member of a multidisciplinary team, leading projects and people successfully in a dynamic-paced team environment.
  • Has an affinity for results-based approaches to documentation, quality and consistency in the execution of all duties


Additional Requirements:
  • Must be available to support weekend, holiday, emergency, and after-hour operational responsibilities
  • Able to lift 50-lbs and/or maneuver vivarium equipment, and work from a standing position for prolonged time periods and perform repetitive motion tasks
  • Duties, responsibilities, and activities may change based on business needs and unanticipated shifts

Company Description:
Ambys Medicines is a biotechnology company focused on discovering and developing regenerative and restorative therapies for people with advanced liver disease. Founded by world-renowned experts in liver disease and regenerative medicine, Ambys is pioneering the application of novel modalities including cell and gene therapy, and gain-of-function drug therapy, to meet the urgent need for treatments that have the potential to restore liver function and prevent the progression to liver failure across multiple liver diseases that are untreatable or poorly treated today. Ambys was launched in 2018 by Third Rock Ventures and Takeda Pharmaceuticals with $140M in starting capital and is headquartered in South San Francisco, California.


To apply: https://grnh.se/9a3b424e2us
For more information, email: Krystle Okialda

(Posted 7/28/20)


Title: Research Associate II at Biomere
Location: Richmond, CA

GENERAL SUMMARY
Research Associate II works under the direct supervision of the Site Head along with the general guidance of the Scientists. Research Associate II are proficient in animal procedures/animal husbandry, colony management, grant, internal, and/or contract research studies according to the study protocols and the company guidelines and standard operating procedures (SOPs).

Click here for more information

MAJOR RESPONSIBILITIES

  • Maintains animal room records including, but not limited to animal identification, cage side observations/clinical observations and environmental parameters (e.g. temperature, humidity). Observes, records and reports atypical findings to veterinary staff and/or senior personnel.
  • Independently reads and understands study protocols and relevant SOPs prior to performing associated duties on designated research projects;
  • Performs all aspects of a study cycle for grant, internal, and/or contract research studies including, but not limited to:
    • Primary Technician role and responsibility;
    • receipt, distribution and husbandry of animals;
    • orders materials and supplies as required for projects;
    • prepares forms and generates study books;
    • prepares procedure rooms with all necessary supplies, materials and equipment required for projects;
    • verifies drugs/agents prior to use and calculates dose administrations;
    • performs dosing regimen, blood collection, frequency of sample, euthanasia, tissue collection and data collection;
    • uses anesthetics for unconscious and/or surgical procedures;
    • monitors grant, internal, and/or contract research studies in progress and clinically evaluates;
    • observes, records and reports atypical findings to veterinary staff or senior personnel;
    • critically evaluates data; tabulate, graph and perform basic statistical analysis;
    • performs data quality control review according to SOPs or study protocols;
    • may interact with clients to provide necessary information about study.
  • May perform in vitro assays including, but not limited to:
    • RNA/DNA purification;
    • Real-time PCR/RT-PCR;
    • PCR;
    • Reagent and dose formulations for in vivo studies;
    • ELISA, ELISPOT;
    • Multicolor flow cytometry (cell preparation and analysis);
    • Preparation of virus stock, virus titration, antibody neutralization, and T-cell assays;
    • Cell preparation and culture (human and animal cell isolation, magnetic bead cell purification);
    • Serum chemistries and CBCs;
    • Additional assay system development based on project needs
  • With guidance from senior scientific staff, may serve as a Study Director to conduct assigned research studies of basic complexity including, but not limited to:
    • Study Director role and responsibility according to SOPs;
    • generates study protocols, study amendments and study timelines;
    • generates IACUC protocols, IACUC amendments, and serve as the Principal Investigator on IACUC protocols;
    • may participate in the proposal management and budgetary process,
    • orders materials and supplies as required for projects;
    • generates study calendars (and matrices if applicable);
    • may direct study performance including the oversight of primary technicians and the QC of data.
    • may review, interpret and present data as applicable for assigned studies;
    • generates Data Submission, Final Reports and/or Summary Reports;
  • May review/edit company guidelines and SOPs.
  • May work directly with Scientists and Scientific Directors on assigned projects.
  • May acquire Designated Trainer role and assist with personnel training including training for technical procedures and competency testing.
  • Comprehends procedures and performs tasks according to company policies and SOPs.
  • Complies with all regulatory guidelines, occupational health as well as health and safety programs, in accordance with company policies and procedures.
  • Performs other related Research Associate I duties as required.


MINIMUM QUALIFICATIONS:
  • Education/Experience: Bachelors of Science degree in a Life Sciences discipline and 5 years related experience OR
  • High School diploma/GED and 8 years directly related work experience in laboratory animal husbandry and technical skills as detailed above required.
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • Certification/Licensure: AALAS Certification at the LAT level preferred.
  • Other: Basic computer skills required.

To apply, please email: HumanResources@biomere.com

(Posted 2/14/20)


Title: Veterinary Technician I at Biomere
Location: Richmond, CA

GENERAL SUMMARY
Veterinary Technician I work under the direct supervision of the Site Lead and general guidance of the COO and veterinary team. Veterinary Technician I assist veterinary staff in the documentation and veterinary clinical care of all laboratory animal health cases. May also perform technical in-life procedures for grant, internal, and/or contract research studies according to the study protocols and to the company guidelines and standard operating procedures (SOPs).

Click here for more information

MAJOR RESPONSIBILITIES

  • Assist in the documentation and veterinary clinical care of all laboratory animal health cases identified by technical staff and/or veterinarian.
  • Performs routine veterinary, technical and husbandry skills including but not limited to the following:
    • administer medications by oral, topical and injectable routes of administration;
    • bandage/wrapping techniques;
    • nail/teeth clipping/trimming;
    • venipuncture techniques;
    • verifies drugs/medications prior to use and calculates dose administrations;
    • proficient animal restraint techniques;
    • monitor critical care animals (i.e., place IVs, monitor fluids, etc.);
    • specimen collection such as blood and feces;
    • perform diagnostic testing on samples such as parasite checks and identification.
  • Monitors animal health, by performing rounds, responding to animal health reports, and by following detailed schedules.
  • Under minimal supervision, triage and assess animal health, provide immediate care to emergency cases.
  • Performs minor surgical procedures.
  • Generates animal treatment records and perform, track and schedule follow-ups.
  • Consult with clinical veterinarian on treatment options.
  • Follow Behavior and Enrichment team guidance for small animal acclimation and enrichment practices
  • Maintains animal room records including, but not limited to animal identification, cage side observations/clinical observations and environmental parameters (e.g. temperature, humidity). Observes, records and reports atypical findings to veterinary staff and/or senior personnel.
  • Maintains appropriate medical records for each animal in accordance with study and regulatory requirements. Assist in maintaining accurate record keeping procedures for the laboratory animal medicine department.
  • Maintain and follow complex procedures to ensure appropriate animal health and treatment.
  • Assist in keeping inventory and monitoring expiration dates of veterinary supplies.
  • May be responsible for tissue sampling, routine animal manipulations and administration of fluids or other treatments as required in collaboration with the study director and Research Associates.
  • Assist in surgery and peri-surgery care (e.g. provide and monitor anesthesia, prepare sterile surgical packs, administer supportive therapy).
  • Independently reads and understands study protocols and relevant SOPs prior to performing associated duties on designated research projects.
  • May perform aspects of a study cycle for grant, internal, and/or contract research studies including, but not limited to technical in-life procedures.
  • May review/edit company guidelines and SOPs.
  • May acquire Designated Trainer role and assist with personnel training including training for technical procedures and competency testing.
  • Comprehends procedures and performs tasks according to company policies and SOPs.
  • Complies with all regulatory guidelines, occupational health as well as health and safety programs, in accordance with company policies and procedures.
  • Performs other related Research Associate I duties as required.


MINIMUM QUALIFICATIONS:
  • Education/Experience: Bachelors of Science degree in a Life Sciences discipline and two (2) years related experience OR
  • CVT/LVT/RVT certification and two (2) years directly related work experience in laboratory animal husbandry and technical skills as detailed above OR
  • High School diploma/GED and four (4) years directly related work experience in laboratory animal husbandry and technical skills as detailed above required.
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • Certification/Licensure: AALAS Certification at the LAT level preferred.
  • Other: Basic computer skills required.

To apply, please email: HumanResources@biomere.com

(Posted 2/14/20)


Title: Animal Research Staff Trainer (4163U) at University of California, Berkeley
Job ID: 5965
Location: Main Campus-Berkeley, CA

Responsibilities
Curriculum Design
Direct Training
Training Facilitation for Other Subject Matter Experts
Training Assessment
Quality Assurance

Click here for more information

About Berkeley
At the University of California, Berkeley, we are committed to creating a community that fosters equity of experience and opportunity, and ensures that students, faculty, and staff of all backgrounds feel safe, welcome and included. Our culture of openness, freedom and belonging make it a special place for students, faculty and staff.

The University of California, Berkeley, is one of the world’s leading institutions of higher education, distinguished by its combination of internationally recognized academic and research excellence; the transformative opportunity it provides to a large and diverse student body; its public mission and commitment to equity and social justice; and its roots in the California experience, animated by such values as innovation, questioning the status quo, and respect for the environment and nature. Since its founding in 1868, Berkeley has fueled a perpetual renaissance, generating unparalleled intellectual, economic and social value in California, the United States and the world.

We are looking for equity-minded applicants who represent the full diversity of California and who demonstrate a sensitivity to and understanding of the diverse academic, socioeconomic, cultural, disability, gender identity, sexual orientation, and ethnic backgrounds present in our community. When you join the team at Berkeley, you can expect to be part of an inclusive, innovative and equity-focused community that approaches higher education as a matter of social justice that requires broad collaboration among faculty, staff, students and community partners. In deciding whether to apply for a position at Berkeley, you are strongly encouraged to consider whether your values align with our Guiding Values and Principles, our Principles of Community, and our Strategic Plan.


Departmental Overview
The Office of Laboratory Animal Care (OLAC) ensures the health and wellbeing of animals used for research and teaching through the provision of veterinary care and oversight, animal husbandry (if not done by the PI), research support services, and training. In addition, OLAC is in charge of animal purchases and acquisition, husbandry and veterinary care, animal shipping, pharmacy and animal supply purchases, and accessing animal facilities.

Responsibilities

Curriculum Design:
  • Design curriculum for supported undergraduate and graduate students, laboratory staff, principal investigators and others as directed by the Supervisor, OLAC Director or ACUC/OACU. Collaborate with others performing training to ensure consistency.
  • Collaborate with veterinary staff to assist and facilitate training that they provide.
  • Lead training material creation through collaboration with management, veterinary staff, process, operations and compliance teams.
  • Measure, interpret and improve training effectiveness, identify and implement opportunities to reduce training time.
  • Incorporate product updates and determine how changes are reflected in materials by updating facilitator and participant guides, learning checks and agendas.
  • Act as subject matter expert in all animal care programs and products.
  • Facilitate other subject matter expert training, including veterinary staff and visiting investigators.
  • Collaborate with project teams by developing ideas, supporting processes and suggesting improvements.
  • Conduct and participate in Train the trainer sessions.

Direct Training:
  • Provide direct training using a variety of techniques including blended learning and adult learning principles (visual, auditory and kinesthetic). Oversee didactic and on the job training activities that are performed independently.
  • Ensure classroom logistics such as materials, equipment, supplies and systems access are organized.
  • Identify training needs of research staff and students and ensure necessary training is conducted; consult on and assist with same needs for OLAC staff.
  • Notify veterinary staff of any deficiencies in animal care related to deficiencies in knowledge and training.
  • Autonomously lead training sessions for students and laboratory personnel regarding basic animal care and peri-veterinary skills (ie handling, injections, aseptic technique, anesthesia, euthanasia); consult on and assist with applicable training for OLAC staff.
  • Coordinate and lead facility orientations for new animal use personnel in collaboration with EH&S and OLAC husbandry personnel.
  • Consult with partners (OLAC management, investigative staff, ACUC/OACU) for questions regarding training needs, materials and/or policy and procedures, including communication in the form of user emails, facility signage, town hall meetings, website.
  • Assist in maintaining training animal colony and animal use protocol.
  • Practice and maintain technical skill sets and procedures, further self-training on new and established techniques.

Training Facilitation for Other Subject Matter Experts:
  • Facilitate, help plan and schedule didactic and on the job training performed by veterinary staff or other subject matter experts, including vendors.
  • Ensure applicable pre-requisites are met.
  • Ensure classroom logistics such as materials, equipment, supplies and systems access are organized.

Training Assessment:
  • Evaluate trainee progress through formal competency reviews and implement performance improvement interventions as needed. Assist Animal Care Staff Trainer in conducing performance assessments gauging readiness and approval for new hire certification.

Quality Assurance:
  • Partner with quality assurance team to ensure training and quality assurance standards are aligned (ie sanitation, biosecurity, documentation).
  • Document training as required by regulations.
  • Performs other duties as assigned.
  • Applies professional training and development skills to resolve and address a wide range of training issues and needs assessments.
  • May support faculty to improve teaching and learning outcomes.
  • May consult with instructors to determine methods for delivery of course content and effective use of technology.
  • Develops new training programs and courses in response to campus' training needs.
  • Designs and conducts more complex training programs to address issues of diverse scope that are aligned with campus strategies.
  • Demonstrates good judgment in selecting methods and techniques for delivering training and development programs.
  • Interacts with senior internal and external personnel.
  • Normally receives little direction on on-going training assignments.
  • Receives general instructions on new training program assignments, projects and initiatives.
  • Conducts needs analysis and evaluates effectiveness of training programs.
  • Works in a collaborative manner with others in a diverse environment and at all levels in the organization to prioritize work assignments, conduct analysis and develop recommendations.
  • May assume responsibility for specific training programs and initiatives.

To apply, and for more information: https://jobs.berkeley.edu/job-listings/external-applicants - keyword 5965

(Posted 2/13/20)

     

Title: Sr. Technologist & Trainer at Charles River Laboratories (CRL)
Location: Hollister, CA

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

JOB SUMMARY
We are seeking a Sr. Technologist & Trainer for our Research Models Production site located in Hollister, California.

This individual will serve as site Animal Welfare specialist. He/she will also provide training to departmental staff on all levels of husbandry and specialized production tasks requiring technical skills following SOPs. He/she will assume primary responsibility for maintenance and auditing of records relating to inbred models.

Click here for more information

ESSENTIAL DUTIES AND RESPONSIBILITIES:

  • Serves as site Animal Welfare specialist.
  • Investigates animal welfare issues, discuss with welfare team; makes recommendations as needed for disciplinary action.
  • Communicates any actions to Corporate Animal Welfare.
  • Participates on behalf of site at annual AWS retreats.
  • Trains departmental staff on all levels of husbandry and production tasks including feeding, watering, and cleaning cages as required.
  • Ensures proper breeding procedures.
  • Maintains appropriate levels of assigned specialized rodent breeds, including nudes, inbred, and SCIDS.
  • Trains departmental staff on specialized tasks in one or more of the following areas: packing and shipping animals to customer, performing animal surgeries; and/or creating sterile water supplies as assigned.
  • Trains departmental staff in monitoring animal health visually and follow swab and health monitoring schedules.
  • Trains personnel in keeping accurate departmental and isolator records. Participates in preparation of reports, offers, and completes customer paperwork.
  • Performs quarterly audits of each inbred room.
  • Maintains weekly record keeping of inbred books. Maintain monthly/quarterly inbred trees.
  • Understands, complies with and trains personnel in SOPs pertaining to specific area. Provides input into the creation/revision of SOPs and assists in the implementation and training of new SOPs.
  • Strictly follows all procedures necessary to maintain the isolator and/or barrier room barrier.
  • Performs all other related duties as assigned.

MINIMUM REQUIREMENTS:
  • High School Diploma or General Education Diploma (G.E.D.)
  • 1 year of training experience

PREFERRED QUALIFICATIONS:
  • Bachelor's degree in Animal Science or a related field.
  • 1-2 years of training and animal welfare experience
  • AALAS Certification

About Research Models & Services
Fundamental to basic research and discovery is the use of in vivo models to help identify disease targets and determine potential biological pathways that regulate the condition. As the world’s leader in the production and distribution of the highest quality research animal, with 1 out of 2 animal models produced for preclinical research globally, we understand the importance of this step. With seven decades of experience, our expertise is unmatched, allowing us to provide you with the perfect model, including disease-specific and preconditioned options, for basic research and beyond.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2018.

Equal Employment Opportunity

Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet


To apply, submit application here and send your resume to Nancy.Burke@crl.com

(Posted 1/30/20)

     

Title: Animal Care/Husbandry Tech 1 - GEMS (EG) at Charles River Laboratories (CRL)
Location: Hollister, CA

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

JOB SUMMARY
We are seeking an entry level Animal Care & Breeding Technician for our Research Models and Services (RMS) site located in Hollister, California.

Click here for more information

ESSENTIAL DUTIES AND RESPONSIBILITIES:

  • Perform routine animal husbandry duties and monitor daily health and welfare to maintain quality and health of animals.
  • Handle, transfer and distribute animals, supplies and waste as needed to and from work area(s).
  • Perform physical environment housekeeping duties and production operations according to Good Manufacturing Practices (cGMPs) and/or Standard Operating Procedures (SOPs).
  • Maintain recordkeeping pertaining to equipment operation, animal or supply area inventories. Strictly follow all procedures necessary to maintain the isolator and/or barrier room barrier.
  • Operate equipment and use supplies according to safety guidelines. Perform all job-related duties in accordance with company safety procedures.
  • Strictly follow all procedures necessary to maintain the isolator and/or barrier room
  • Perform all other related duties as assigned.

MINIMUM REQUIREMENTS:
The following are minimum requirements related to the Animal Care & Breeding Technician position.
  • High school diploma or General Education Degree (G.E.D.).
  • Minimum 6 months’ experience working in a regulated environment, where tasks are performed according to standard operating procedures, rules, or regulations, where efficiency and accuracy are critical, and keeping accurate and thorough records are required (such as food service, CNA, etc. under FDA, Health Dept. regulations, etc.).
  • Demonstrated ability to perform in a physically demanding role including standing, lifting up to 50 pounds, moving about, and ascend and descend and work from a platform ladder.
  • Participation in Weekend and Holiday Schedule Rotation Required.

PREFERRED QUALIFICATIONS:
  • One (1) year of related experience in and/or training in animal husbandry.
  • AALAS certification at the Assistant Technician or its equivalent.

About Research Models & Services
Fundamental to basic research and discovery is the use of in vivo models to help identify disease targets and determine potential biological pathways that regulate the condition. As the world’s leader in the production and distribution of the highest quality research animal, with 1 out of 2 animal models produced for preclinical research globally, we understand the importance of this step. With seven decades of experience, our expertise is unmatched, allowing us to provide you with the perfect model, including disease-specific and preconditioned options, for basic research and beyond.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2018.

Equal Employment Opportunity

Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet


To apply, submit application here and send your resume to Nancy.Burke@crl.com

(Posted 1/30/20)

NORTHERN CALIFORNIA BRANCH OF THE AMERICAN ASSOCIATION FOR LABORATORY ANIMAL SCIENCE  P.O. BOX 876 San Leandro, CA 94577 © 2019


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